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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
44.55
Human Site:
S229
Identified Species:
61.25
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S229
T
T
H
V
L
R
L
S
W
S
P
D
G
H
Y
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S229
T
T
H
V
L
R
L
S
W
S
P
D
G
H
Y
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S349
T
T
H
V
L
R
L
S
W
S
P
D
G
H
Y
Dog
Lupus familis
XP_543550
1017
111618
S229
T
T
H
V
L
R
L
S
W
S
P
D
G
H
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
S229
T
T
H
V
L
R
L
S
W
S
P
D
G
H
Y
Rat
Rattus norvegicus
NP_001129232
1015
111665
S229
T
T
H
V
L
R
L
S
W
S
P
D
G
H
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
S229
T
T
H
V
L
R
L
S
W
S
P
D
G
H
Y
Frog
Xenopus laevis
Q8QFR2
1013
112021
S229
T
T
H
V
L
R
L
S
W
S
P
D
G
H
Y
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
S229
T
T
H
V
L
R
L
S
W
S
P
D
G
Q
Y
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
S229
T
T
H
V
L
R
L
S
W
S
P
D
G
Q
Y
Fruit Fly
Dros. melanogaster
O17468
1047
113397
S227
T
T
H
I
L
R
L
S
W
S
P
D
G
Q
Y
Honey Bee
Apis mellifera
XP_001122939
838
91355
W78
A
C
V
N
C
V
R
W
S
N
T
G
L
L
A
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
I175
R
I
T
V
L
N
D
I
Q
L
P
V
K
G
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
K204
S
D
W
S
L
A
H
K
T
E
G
H
W
T
K
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
G215
S
T
F
F
R
R
L
G
W
S
P
C
G
H
F
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
G80
C
S
M
S
R
H
T
G
S
I
T
C
V
K
F
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
K229
T
S
I
S
V
P
F
K
H
S
P
L
T
T
Y
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
93.3
86.6
0
20
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
93.3
93.3
6.6
20
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
6.6
N.A.
53.3
0
26.6
P-Site Similarity:
N.A.
13.3
N.A.
66.6
13.3
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
0
0
0
0
6
0
0
0
0
0
0
0
0
6
% A
% Cys:
6
6
0
0
6
0
0
0
0
0
0
12
0
0
0
% C
% Asp:
0
6
0
0
0
0
6
0
0
0
0
65
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% E
% Phe:
0
0
6
6
0
0
6
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
0
0
12
0
0
6
6
71
6
0
% G
% His:
0
0
65
0
0
6
6
0
6
0
0
6
0
53
0
% H
% Ile:
0
6
6
6
0
0
0
6
0
6
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
0
0
6
6
6
% K
% Leu:
0
0
0
0
77
0
71
0
0
6
0
6
6
6
6
% L
% Met:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
6
0
6
0
0
0
6
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
6
0
0
0
0
83
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
6
0
0
0
0
18
0
% Q
% Arg:
6
0
0
0
12
71
6
0
0
0
0
0
0
0
0
% R
% Ser:
12
12
0
18
0
0
0
65
12
77
0
0
0
0
0
% S
% Thr:
71
71
6
0
0
0
6
0
6
0
12
0
6
12
0
% T
% Val:
0
0
6
65
6
6
0
0
0
0
0
6
6
0
0
% V
% Trp:
0
0
6
0
0
0
0
6
71
0
0
0
6
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
71
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _